Symptoms include shortness of breath (with activity or at rest), difficulty breathing while lying down (orthopnea), and swelling in the legs or abdomen (peripheral edema). Cardiac amyloidosis is a cause of heart failure many people don’t know about. Learn symptoms of this condition and when to seek care.

Diagnosis can take time, as many people present with symptoms of heart failure, which are treated, while the underlying cause may be difficult to identify.